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Details van artikel 6 van 19 gevonden artikelen
| Titel: |
Consensus Based Validation of Membrane Porins |
| Auteur: |
A.V.S.K. Mohan Katta Rajeshwari Marikkannu Rajiv V. Basaiawmoit Sankaran Krishnaswamy |
| Verschenen in: |
In silico biology |
| Paginering: | Jaargang 4 (2005) nr. 4 pagina's 549-561 |
| Jaar: |
2005-02-28 |
| Inhoud: |
Porins are outermembrane β-barrel proteins. They have varied biological functionality ranging from phage receptors, immunogenicity, pathogenicity to apoptosis. However, only a small number has been structurally and functionally characterised. A validation mechanism and a database of porins would be useful for target selection in proteomics and structural genomics work. Here we report a validation mechanism developed for membrane porins. A database server for porins, PRNDS, has been created containing experimentally proven porins and likely putative porins. Each porin is validated and ranked using a weighted scoring system developed based on six, structure and sequence based criteria. The server also predicts possible porins. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 6 van 19 gevonden artikelen
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