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Details for article 2 of 19 found articles
| Title: |
Annotating Significant Pairs of Transcription Factor Binding Sites in Regulatory DNA |
| Author: |
Katja Rateitschak Tobias Müller Martin Vingron |
| Appeared in: |
In silico biology |
| Paging: | Volume 4 (2005) nr. 4 pages 479-487 |
| Year: |
2005-02-28 |
| Contents: |
In the presented work we search for transcription factor binding sites (BS) by including additional information about typical BS patterns. The new proposed score combines the ordinary profile score based on TRANSFAC-matrices together with a score based on pairs of BS. The latter score positively weights pairs of BS that tend to occur together in many regulatory DNA-sequences, in contrast to a random background model. The empirical BS pair frequencies result from our evaluation of a large dataset of orthologous genes. |
| Publisher: |
IOS Press |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 2 of 19 found articles
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