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Details for article 10 of 11 found articles
| Title: |
Rapid Detection of Conserved Regions in Protein Sequences Using Wavelets |
| Author: |
Arun Krishnan Kuo-Bin Li Praveen Issac |
| Appeared in: |
In silico biology |
| Paging: | Volume 4 (2004) nr. 2 pages 133-148 |
| Year: |
2004-08-24 |
| Contents: |
We present an algorithm to detect protein sub-structural motifs from primary sequence. The input to the algorithm is a set of aligned multiple protein sequences. It uses wavelet transforms to decompose protein sequences represented numerically by different indices (such as polarity, accessible surface area or electron-ion integration potentials of the amino acids). The numerical representation of a protein sequence has significant correlation with its biological activity, thus common motifs are expected to be observable from the wavelet spectrum. The decomposed signals are then up-sampled and similarity search techniques are used to identify similar regions across all the proteins at multiple scales. Results indicate that wavelet transform techniques are a promising approach for rapid motif detection. |
| Publisher: |
IOS Press |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 10 of 11 found articles
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