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  HLA B-27 subtypes in turkish patients with spondyloarthropathy and healthy controls
 
 
Titel: HLA B-27 subtypes in turkish patients with spondyloarthropathy and healthy controls
Auteur: Fatma Savran Oguz
Lale Ocal
Ali Sarper Diler
Hilmi Ozkul
Faruk Asicioglu
Esen Kasapoglu
Gokay Bozkurt
Meral Konice
Mahmut Carin
Verschenen in: Disease markers
Paginering: Jaargang 20 (2005) nr. 6 pagina's 309-312
Jaar: 2005-01-18
Inhoud: The frequency and the distribution of HLA-B27 subtypes in spondylarthropathy (SpA) patients and controls were investigated in a sample Turkish population. B27 subtyping was performed by PCR-SSP method in two groups: 49 unrelated HLA-B27 positive Turkish patients with the diagnosis of SpA according to the European Spondyloarthropathy Study Group Criteria, and 55 HLA-B27 positive healthy controls. The frequency of HLA-B*27 was 2.6% in the Turkish population, and B*2705 was the predominant allele among patients with SpA. The difference was mainly between male patients and male controls The proportion of B*2705 among B27-positive patients and controls was significantly different (P = 0.02). Our study supports other reports from different populations which showed that B*2705 and B*2702 were more frequent in Caucasian patients with SpA.
Uitgever: IOS Press
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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