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| Titel: |
Ascending the learning curve - MSI testing experience of a six-laboratory consortium |
| Auteur: |
Lindor, Noralane M. Smalley, Regenia Barker, Melissa Bigler, Jeannette Krumroy, Lisa M. Lum-Jones, Annette Plummer, Sarah J. Selander, Teresa Thomas, Sushma Youash, Michelle Seminara, Daniela Casey, Graham Bapat, Bharati Thibodeau, Stephen N. |
| Verschenen in: |
Disease markers. Section A, Cancer biomarkers |
| Paginering: | Jaargang 2 (2006) nr. 1-2 pagina's 5-9 |
| Jaar: |
2006-07-13 |
| Inhoud: |
According to recently published guidelines, microsatellite instability (MSI) testing of colorectal cancers may be clinically indicated on a significant proportion of all colorectal tumors. To date, nothing has been published regarding the reproducibility of MSI testing between laboratories. We present MSI quality control activities experience of a six center multinational consortium, as laboratories developed competency with MSI testing and interpretation. The aim of this paper is to share lessons learned and to describe the final concordance rates in scoring MSI markers within this consortium. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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