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Details for article 1 of 37 found articles
| Title: |
A novel test for identifying genes involved in aldehyde detoxification in the yeast. Increased sensitivity of superoxide-deficient yeast to aldehydes and their metabolic precursors |
| Author: |
Tomasz Biliński Magdalena Kwolek Ewelina Sas Marta Krynicka Sabina Koziol Alina Owsiak-Teleon Anna Krzepilko Grzegorz Bartosz |
| Appeared in: |
BioFactors |
| Paging: | Volume 24 (2006) nr. 1-4 pages 59-65 |
| Year: |
2006-01-16 |
| Contents: |
A novel test for the identification of genes involved in aldehyde metabolism is proposed, based on detection of altered sensitivity of the yeast to corresponding alcohols, metabolic precursors of the aldehydes. This attitude enabled to an unexpected detection increased sensitivity of mutants devoid of CuZn-superoxide dismutase (CuZnSOD) to allyl alcohol (precursor of acrolein) and nonenol. We interpret this finding as due to inactivation of some important element of aldehyde detoxification by increased flux of superoxide in ΔCuZnSOD mutants. |
| Publisher: |
IOS Press |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 1 of 37 found articles
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