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| Titel: |
Inhibitory activity of shiitake flavor against platelet aggregation |
| Auteur: |
Shoichiro Shimada Koji Komamura Hitomi Kumagai Hidetoshi Sakurai |
| Verschenen in: |
BioFactors |
| Paginering: | Jaargang 22 (2004) nr. 1-4 pagina's 177-179 |
| Jaar: |
2004-12-30 |
| Inhoud: |
Sulfuric-flavored compounds were extracted from shiitake (Lentinus edodes) and their inhibitory activity against platelet aggregation was investigated. Platelet aggregation induced by arachidonic acid and U-46619, the analog of thromboxane A_2, was inhibited by the essential oil from shiitake that contained lenthionine as a major sulfuric compound. This result indicates that the inhibitory site of the shiitake flavor compounds would be different from that of garlic-flavor compounds because the latter inhibits the passage between arachidonic acid and thromboxane A_2. The effect of the synthesized lenthionine was almost equivalent to that of the essential oil, which indicates that the inhibitory activity of the essential oil from shiitake would be mainly attributed to lenthionine. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 47 van 69 gevonden artikelen
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