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Details for article 2 of 82 found articles
| Title: |
Absorption and metabolism of delphinidin 3-O-ß-D-glucoside in rats |
| Author: |
Takashi Ichiyanagi M. Mamunur Rahman Yoshiki Kashiwada Yasumasa Ikeshiro Yasuo Shida Yoshihiko Hatano Hitoshi Matsumoto Masao Hirayama Tetsuya Konishi |
| Appeared in: |
BioFactors |
| Paging: | Volume 21 (2004) nr. 1-4 pages 411-413 |
| Year: |
2004-12-30 |
| Contents: |
Anthocyanins, kind of flavonoids (FL) found in plants and vegetables, are known to have varieties of physiological functions. In the present study, we examined absorption and metabolism of delphinidin 3-O-β-D-glucoside (Dp3G) in rats. Dp3G appeared in the plasma at 15 min after oral administration as an intact glucosidic form. The plasma level also showed another peak at 60~min. One metabolite peak was detected in the plasma and the structure was assigned as 4'-O-methyl Dp3G (MDp3G) by NMR and MS. The metabolite was also identified in several tissues as a major metabolite especially in the liver. No 3'-O-methyl Dp3G was detected in any tissues, therefore, 4'-OH methylation is the main path of Dp3G metabolism in rats. This finding generalized the metabolic formation of FL having pyrogallol B ring because it has been reported that FL having catechol structure produced 3'-O-methyl-derivatives, but FL having pyrogallol structure produced 4'-O-methyl-derivatives. |
| Publisher: |
IOS Press |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 2 of 82 found articles
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