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| Titel: |
Analysis of HMPAO SPECT scans in head injury using Statistical Parametric Mapping |
| Auteur: |
E.A. Stamatakis J.T.L. Wilson D.J. Wyper |
| Verschenen in: |
Behavioural neurology |
| Paginering: | Jaargang 12 (2001) nr. 1-2 pagina's 29-37 |
| Jaar: |
2001-04-01 |
| Inhoud: |
The paper examines the ability of Statistical Parametric Mapping (SPM) to contribute towards the quantitative analysis of HMPAO SPECT images containing lesions. A validation study is described in which SPECT images were created that contained synthetic lesions and were analysed with SPM. The study established a set of guidelines concerning the alignment, smoothing, and statistical analysis of images. These were then applied to analysis of SPECT scans from head injured patients. A demonstration is given of the use of SPM to identify localised blood flow abnormalities associated with cognitive deficits after head injury. Correlations between blood flow abnormalities and a test of visual memory are illustrated. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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