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                                       Details van artikel 5 van 8 gevonden artikelen
 
 
  Role of the striatum and the cerebellum in motor skill acquisition
 
 
Titel: Role of the striatum and the cerebellum in motor skill acquisition
Auteur: Markus M. Schugens
Caterina Breitenstein
Hermann Ackermann
Irene Daum
Verschenen in: Behavioural neurology
Paginering: Jaargang 11 (2001) nr. 3 pagina's 149-157
Jaar: 2001-08-17
Inhoud: Motor skill acquisition was investigated in patients with Parkinson's disease (PD) or cerebellar dysfunction using two sensory-guided tracking tasks. The subjects had to learn to track a visual target (a square) on a computer screen by moving a joystick under two different conditions. In the unreversed task, the horizontal target movements were semi-predictable and could be anticipated. In the reversed task, the horizontal movements of a pointer which had to be kept within the target square were mirror-reversed to the joystick movements. PD patients showed intact learning of the semi-predictable task and reduced learning of the mirror-reversed task; patients with cerebellar dysfunction showed the opposite pattern. These findings are discussed in relation to the differential contribution of the cerebellum and the striatum to motor skill acquisition: the cerebellum appears to participate in the implementation of anticipatory movements, whereas the striatum may be critically involved in types of motor learning which require a high degree of internal elaboration.
Uitgever: IOS Press
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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