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Details for article 11 of 34 found articles
| Title: |
6-HYDROXY-L-NICOTINE FROM ARTHROBACTER NICOTINOVORANS FACILITATE SPATIAL MEMORY FORMATION IN RATS |
| Author: |
LUCIAN HRITCU MARIUS STEFAN MARIUS MIHASAN RODERICH BRANDSCH |
| Appeared in: |
Analele ÿðstinÿðtifice ale universitÿæaÿðtii "Alexandru Ioan Cuza" din Iaÿðsi. Sectiunea II a. Geneticÿæa ÿðsi Biologie Molecularÿæa |
| Paging: | Volume XI (2010) nr. 4 pages 207-2013 |
| Year: |
2010 |
| Contents: |
Effects of 6-hydroxy-L-nicotine derived from nicotine catabolism in Arthrobacter nicotinovorans on learning and memory processes were examined in adult male Wistar rats. 6-hydroxy-L-nicotine (0.3 mg/kg, i.p., 7 consecutive days chronic administration) significantly increased spontaneous alternation in Y-maze task and working memory in radial arm-maze task, suggesting effects on short-term memory, without affecting long-term memory, explored by reference memory in radial arm-maze task. Taken together, our results suggest that 6-hydroxy-L-nicotine sustain memory formation and may provide the opportunity to manage neurological abnormalities in neurodegenerative disease |
| Publisher: |
Editura Universitatii Alexandru Ioan Cuza (provided by DOAJ) |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 11 of 34 found articles
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