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Details for article 6 of 10 found articles
| Title: |
CYP2C9 Gene Analysis of Some Iranian Hypersensitive Patients to Warfarin |
| Author: |
P. Ghadam R. Sharifian Z. Jomeh Farsangi Z. Kianmehr M. Lak |
| Appeared in: |
Pakistan journal of biological sciences |
| Paging: | Volume 12 (2009) nr. 16 pages 1160-1163 |
| Year: |
2009 |
| Contents: |
For the first time in this study, the pharmacogenetic effects of CYP2C9 polymorphism on warfarin sensitivity in some Iranian patients who are on warfarin treatment were shown. The study group consisted of clinically sensitive patients(21 patients) and the control group (37 adult patients). For detection of CYP2C9*2 and CYP2C9*3 variants, a protocol based on restriction fragment length polymorphism based polymerase chain reaction with Eco47I and KpnI was used. In clinically sensitive patients about 81% and in normal response patients about 24.3% carried variant genotypes. |
| Publisher: |
Asian Network for Scientific Information (provided by DOAJ) |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 6 of 10 found articles
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