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Details for article 6 of 13 found articles
| Title: |
Identification of Cytotoxic Compound from Artocarpus communis Leaves Against P-388 Cells |
| Author: |
Puspa D.N. Lotulung Sofa Fajriah Muhammad Hanafi Euis Filaila |
| Appeared in: |
Pakistan journal of biological sciences |
| Paging: | Volume 11 (2008) nr. 21 pages 2517-2520 |
| Year: |
2008 |
| Contents: |
In the course of continuing research for finding bioactive compounds from Indonesian plants, the leaves of Artocarpus communis was extracted by ethanol. This extract partitioned with n-hexane-water (1:4) and then water extract was partitioned with dichloromethane. Dichloromethane extract was purified by column chromatography techniques on silica gel to afford yellow crystal (F-1). Based on LC-MS, 1H-NMR and 13C-NMR (1D and 2D) spectra and compared with previous spectral data, it was identified as prenylated flavonoid, 1-(2,4-dihydroxyphenyl)-3-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-yl] 1-propanone. This compound showed significant cytotoxicity against murine P-388 leukemia cells. |
| Publisher: |
Asian Network for Scientific Information (provided by DOAJ) |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 6 of 13 found articles
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