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  Soluble CD26 and CD30 Plasma Levels in HIV Infected Patients with and Without GB Virus Type C Coinfection
 
 
Titel: Soluble CD26 and CD30 Plasma Levels in HIV Infected Patients with and Without GB Virus Type C Coinfection
Auteur: Haji-Molla-Hoseini Mostafa
Pourfathollah Ali-Akbar
Soheili Zahra
Mohraz Minoo
Amini Sedigheh
Aghaiepour Mahnaz
Samiee Shahram
Nikoogoftar Mahin
Moghtadaie Mina
Verschenen in: Pakistan journal of biological sciences
Paginering: Jaargang 10 (2007) nr. 12 pagina's 2014-2019
Jaar: 2007
Inhoud: </b> GB virus type C (GBV-C) probably influences HIV infection associated disease by either directly inhibiting HIV replication or enhancing the immune competence to cope with HIV. Still the definitive mechanisms of this inhibitory effect need to be identified. To address the possibility of immune modulating effects of GBV-C coinfection in HIV patients we evaluated plasma levels of soluble (s) CD26 and CD30 in HIV infected patients with and without GBV-C. Cross-sectional comparison of sCD26 and sCD30 levels among 6 HIV/GBV-C coinfected, 11 HIV mono-infected and 13 healthy controls was carried out. We used a commercial EIA to evaluate sCD26 and scD30 and a RT-PCR assay to detect active GBV-C infection. The Mann-Whitney U test was used for statistical analysis. No statistically significant differences were observed in levels of sCD26 and sCD30 in plasma of HIV infected patients with and without GBV-C viremia. GBV-C infection does not appear to influence the sCD26 and sCD30 levels.
Uitgever: Asian Network for Scientific Information (provided by DOAJ)
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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