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Details for article 10 of 28 found articles
| Title: |
Echinococcus Granulosus: A Morphometric and Histopathological Response of Kidney in Rabbits |
| Author: |
T. Akhtar S. Qadir Z. Anwar A. Maqbool |
| Appeared in: |
Pakistan journal of biological sciences |
| Paging: | Volume 1 (1998) nr. 3 pages 154-158 |
| Year: |
1998 |
| Contents: |
Out of forty rabbits (Lepus nigricollis) acclimatized to the optimal condition of animal house, thirty-five were daily inoculated with weekly increasing doses of filtered hydatid cyst fluid of sheep origin for seven weeks. 15 control rabbits were given similar doses of distilled water. Five experimental and three control rabbits were weekly slaughtered and their kidney tissue was fixed in bouins and stained with haematoxylin and eosine. The morphometric findings made and compared with their respective controls, showed significant increase (P<0.001) in the area and volume of glomerules. In the histological preparations of kidney of infected rabbits capillaries of the glomeruli, loops of Henle and lumen of collecting tubules was found dilated. The space between the Bowman`s capsule diminished while in some it increased due to the shrinkage of the glomerular capillaries. In the proximal and distal tubules the cell membranes towards the lumen were destroyed while those away from it were diffused. The cells were hypertrophied with colloidal disintegration, vacuolation and in some cases margination. The nuclei were either hypertrophied with vacuolation or pyknotic and darkly stained. The arteries were thick walled and surrounded by fibrotic tissues while the veins were full of red blood cells. Hemorrhage was present in different regions. There was an overall infiltration of leukocytes. It was noted that the damage in the kidney tissues increased with the increase in dose and time. |
| Publisher: |
Asian Network for Scientific Information (provided by DOAJ) |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 10 of 28 found articles
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