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                                       Details van artikel 38 van 112 gevonden artikelen
 
 
  Effect of Oral Administration of Fenitrothion on Biochemical and Hematological Parameters in Rats
 
 
Titel: Effect of Oral Administration of Fenitrothion on Biochemical and Hematological Parameters in Rats
Auteur: Simin Afsha
Reza Heidari
Amir Abbas Farshid
Minoo Ilkhanipour
Verschenen in: Pakistan journal of biological sciences
Paginering: Jaargang 11 (2008) nr. 13 pagina's 1742-1745
Jaar: 2008
Inhoud: The aim of this study was to evaluate the effects of acute exposure to various doses of fenitrothion (FNT) on level of serum glucose, total protein, triglycerides (TG), total cholesterol (TC) and some hematological parameters. The study was conducted on 8-week old male Wistar rats that divided into four groups (three experimental groups and one control group), were treated orally with different doses (25, 50 and 100 mg kg-1) of fenitrothion for 28 consecutive day. After treatment, blood samples were collected for biochemical and hematological studies. Present results demonstrated that exposed groups led to significant dose-dependent increase in serum glucose and cholesterol levels. Significant decrease was observed in some hematological parameters [Red Blood Cell (RBC) counts, Hemoglobin (Hb), Haematocrite (Ht) and Mean Corpuscular Hemoglobin (MCH) values]. Serum total protein and triglycerides were also decreased not significantly in exposed groups when compared with control. Generally, the degrees of observed variations were found to be dose dependent.
Uitgever: Asian Network for Scientific Information (provided by DOAJ)
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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