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Details van artikel 18 van 28 gevonden artikelen
| Titel: |
Rat liver tyrosine aminotransferase activity and induction by dexamethasone upon cadmium intoxication |
| Auteur: |
Dunđerski Jadranka S. Predić Jelena Čvoro Aleksandra Matić Gordana M. |
| Verschenen in: |
Archives of biological sciences |
| Paginering: | Jaargang 55 (2003) nr. 1-2 pagina's 3-7 |
| Jaar: |
2003 |
| Inhoud: |
This study was focused on Cd effects on basal and dexamethasone-induced tyrosine aminotransferase (TAT) activity in the rat liver cytosol. Cadmium (Cd), applied in the dose of 2 mg/kg b.w., stimulated both TAT activity and its induction by dexamethasone, inducing the most prominent alterations 24 h after administration. Doses lower than 2 mg Cd/kg b.w. were ineffective while the higher ones (3 and 4 mg Cd/kg b.w) led to the changes similar to those reached by 2 mg Cd/kg. The in vitro application of different Cd concentrations to the liver cytosol rendered the enzyme activity unchanged suggesting that the metal acted at the level of TAT gene transcription. |
| Uitgever: |
Srpsko biološko društvo, Institut za biološka istraživanja "Siniša Stanković", Biološki fakultet Univerziteta u Beogradu, Institut za primenu nuklearne energije u poljoprivredi, šumarstvu i veterinarstvu (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 18 van 28 gevonden artikelen
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