|
| << previous | next >> |
Journal description
All volumes of the corresponding journal
All issues of the corresponding volume
All articles of the corresponding issues
Details for article 82 of 88 found articles
| Title: |
The Effects of Pre and Post Training Administration of MK-801 in Dorsal Hippocampus on Learning and Memory in Adult Male Rats |
| Author: |
A.A. Moazedi Z. Valizadeh Gh. A. Parham |
| Appeared in: |
Journal of biological sciences |
| Paging: | Volume 8 (2008) nr. 2 pages 416-420 |
| Year: |
2008 |
| Contents: |
The aim of the present study was to investigate the effects intra-dorsal hippocampus (intraCA1) injection of NMDA receptor noncompetitive antagonists (MK-801) on memory retention using passive avoidance learning. The antagonist was administered pre and post-behavioral training. In the first experiment adult Wistar rats were given saline or MK-801 (1 μg rat-1) 10 min prior to training for 4 days, while in the second experiment saline or MK-801 (1 μg rat-1) were given immediately after training for 4 days. Post-training administration of MK-801 did not affects memory retention, in contrast to pre-training injection of MK-801 which decreased memory retention. The results suggest that pre-training injection of the non competitive antagonist NMDA receptor (MK-801) in hippocampus impaired learning and memory but post-training administration of MK-801 did not effect on learning and memory in passive avoidance learning task.` |
| Publisher: |
Asian Network for Scientific Information, Pakistan (provided by DOAJ) |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 82 of 88 found articles
| << previous | next >> |