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Details for article 14 of 73 found articles
| Title: |
Cerebrospinal Fluid Stem Cell Factor Concentrations in the Children with Meningitis |
| Author: |
Farhad Mashayekhi Zivar Salehi |
| Appeared in: |
Journal of biological sciences |
| Paging: | Volume 7 (2007) nr. 7 pages 1244-1248 |
| Year: |
2007 |
| Contents: |
The aim of this study was to determine the level of Cere Brospinal Fluid (CSF) Stem Cell Factor (SCF) concentrations in the children with acute bacterial and viral meningitis. The presence of SCF in the CSF was confirmed by western blot using anti-SCF antibody as a probe. Using Enzyme Linked Immunosorbent Assay (ELISA), it was shown that the level of CSF SCF in the patients with acute bacterial meningitis is higher than in acute viral meningitis. We have also shown that the concentration of CSF SCF in the patients with acute viral and bacterial meningitis samples was higher than in normal CSF with the same age. It is concluded that CSF could be involved in the pathophysiology of meningitis. SCF may be important in neurogenesis and neural cell survival and provide a basis for future studies related to neuroprotective mechanisms exerted by SCF in meningitis. Moreover, CSF SCF levels can be used in the early diagnosis of meningitis. Similarly, they may be useful adjuncts in differential diagnosis of bacterial and viral meningitis. |
| Publisher: |
Asian Network for Scientific Information, Pakistan (provided by DOAJ) |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 14 of 73 found articles
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