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| Titel: |
Methylprednisolone Induced Histological and Histochemical Changes in the Adrenal Cortex of Rat |
| Auteur: |
S.A. Sakr N. I. El-Desouky S.M. Hanafy |
| Verschenen in: |
Journal of biological sciences |
| Paginering: | Jaargang 2 (2002) nr. 5 pagina's 320-324 |
| Jaar: |
2002 |
| Inhoud: |
In this experiment the effect of the synthetic glucocorticoid, methyl prednisolone on the adrenal cortex of albino rat was investigated by applying histological and histochemical techniques. Animals were orally given methyl prednisolone at a dose level of 1.8 mg/kg/body weight dissolved in sterile saline, 3 times/week for 3 weeks. Histological results revealed atrophy of zona fasciculata, thickness of adrenal capsule and hypertrophy of zona reticularis. Total carbohydrate content of the zona glomerulosa, zona fasiculata and zona reticularis cells showed an obvious decrease after treatment which was prominent after 3 weeks. Total protein content showed a marked decrease in zona glomerulosa and zona fasiculata. On the other hand, the cells of zona reticularis appeared with an increase amount of total protein. |
| Uitgever: |
Asian Network for Scientific Information (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 23 van 40 gevonden artikelen
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