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| Titel: |
Changes in selected parameters of the antioxidant system in radiation damage to the organism |
| Auteur: |
Leos Navratil Jaroslav Racek Renata Havrankova Ladislav Beranek Zuzana Freitinger Skalicka Hana Siffnerova Eva Kantorova |
| Verschenen in: |
Journal of applied biomedicine |
| Paginering: | Jaargang 6 (2008) nr. 4 pagina's 195-201 |
| Jaar: |
2008 |
| Inhoud: |
The target of the present work was a study of the oxidation-reduction system of the organism damagedwith ionizing radiation. The parameters chosen for examination were: the superoxide dismutaseactivity in erythrocytes, the concentration of reduced glutathione in erythrocytes, the activity ofglutathione peroxidase in the total blood, the concentration of malondialdehyde in the blood plasma,and the antioxidant capacity of blood plasma. These parameters were monitored in four groups(patients after radiotherapy, volunteers whose blood was submitted to in vitro irradiation, employees ofa nuclear power plant, and a group of healthy persons). A statistically significant decrease in theGSHPx activity was measured in patients after radiotherapy and in employees of the nuclear powerplant. Results of processing the data obtained by the method of multidimensional analysis of variancesuggest that the dynamics of the changes is comparable in the group of patients after radiotherapy andemployees of the nuclear power plant on the one hand, and in the control group and group of healthyvolunteers whose blood was subjected to in vitro irradiation, on the other. The study demonstratedchanges concerning certain parameters of the oxidation-reduction system after the action of ionizingradiation. |
| Uitgever: |
University of South Bohemia (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 2 van 6 gevonden artikelen
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