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Details van artikel 2 van 6 gevonden artikelen
| Titel: |
Oxime reactivation of acetylcholinesterase inhibited by toxic phosporus ester: In vitro kinetics and thermodynamics |
| Auteur: |
Jiri Patocka Jiri Cabal Kamil Kuca Daniel Jun |
| Verschenen in: |
Journal of applied biomedicine |
| Paginering: | Jaargang 3 (2005) nr. 2 pagina's 91-99 |
| Jaar: |
2005 |
| Inhoud: |
Owing to the threat of organophosphate exposures, not only to pesticides but also to nerve agents, it isvery important to know the whole process of organophosphates-inhibited acetylcholinesterase (AChE, EC3.1.1.7) reactivation. Although current antidotes against organophosphorus intoxications consist also ofprophylactics, AChE reactivators are still needed especially in the case of intoxications with high doses oforganophosphates, for which prophylactic treatment is not effective. For this reason, new AChEreactivators are still being developed. Our work summarizes accurately the whole reactivation process,and offers some help for scientists who are interested in the area of AChE reactivation. |
| Uitgever: |
University of South Bohemia (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 2 van 6 gevonden artikelen
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