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Details van artikel 7 van 11 gevonden artikelen
| Titel: |
Fruit Gum of Aegle marmelos as Pharmaceutical Aid |
| Auteur: |
D.N. Patil A.R. Kulkarni B.S. Patil |
| Verschenen in: |
International journal of pharmacology |
| Paginering: | Jaargang 6 (2010) nr. 1 pagina's 68-71 |
| Jaar: |
2010 |
| Inhoud: |
In the present study have formulated the oral tablets of paracetamol by using Aegle marmelos fruit gum as a binder. The four different tablet formulations were prepared by wet granulation method. The binder concentrations used in the formulation were 2, 4, 6 and 8% w/v of A. marmelos fruit gum, tablets were subjected for evaluation of hardness, friability, drug content uniformity. Preliminary evaluation of granules showed that, 0.71 to 0.77 mm granule size, 29.20 to 30.10° angles of repose and 22.1 to 12.7% fines. Hardness was found in the range of 7.1 to 7.4 kg cm-2, the percent friability was in the range of 1.50 to 0.75%. The tablet showed 97.46 to 98.96% of labeled amount of paracetamol indicating uniformity in drug content, 8 to 18 min disintegration time and more than 90% dissolution in 75 min. Tablets at 6% w/w binder concentration showed more optimum results as tablet binder. The Aegle marmelos gum was found to be useful for the preparation of uncoated tablet dosage form. |
| Uitgever: |
Asian Network for Scientific Information (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 7 van 11 gevonden artikelen
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