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| Titel: |
Screening of Anti-Arthritic, Anti-Inflammatory and Analgesic Activity of a Polyherbal Formulation |
| Auteur: |
S. Meera N.S. Kumar V.S.S.S. Guptatyam |
| Verschenen in: |
International journal of pharmacology |
| Paginering: | Jaargang 4 (2008) nr. 5 pagina's 398-402 |
| Jaar: |
2008 |
| Inhoud: |
Anti-arthritic, anti-inflammatory and analgesic activity of Arthosansar (AS), a polyherbal formulation was evaluated and validated in various animal models. Arthritis was induced by Complete Freund`s Adjuvant (CFA) injection in metatarsal footpad of Sprague-Dawley rats. Degree of inflammation was evaluated by hind paw swelling and body weight, estimation of AST, ALT and TP supported by histopathology of knee joint. AS reduced hind paw swelling, body weight, AST, ALT and TP Histopathology revealed significant reduction in mononuclear infiltration, pannus formation and bone erosion. AS decreased the paw volume in carageenan treated rats. As shows moderate central and peripheral analgesic activities in hot plate method and acetic acid induced writhing method in mice. |
| Uitgever: |
Asian Network for Scientific Information, Pakistan (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 24 van 24 gevonden artikelen
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