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| Titel: |
Protective Role of Tephrosia purpurea Ethanolic Seed Extract on Glycoprotein Components in Streptozotocin Induced Diabetic Rats |
| Auteur: |
Pamu Pavana Subramanian Sethupathy S. Manoharan |
| Verschenen in: |
International journal of pharmacology |
| Paginering: | Jaargang 4 (2008) nr. 2 pagina's 114-119 |
| Jaar: |
2008 |
| Inhoud: |
The aim of the present study was to investigate the beneficial role of Tephrosia purpurea ethanolic seed extract on glycoprotein components in streptozotocin induced diabetic rats. Diabetes mellitus was induced in wistar rats by single intraperitoneal injection of streptozotocin (50 mg kg-1 b.wt.) dissolved in 0.1 M citrate buffer (pH 4.5) after overnight fasting for 12 h. Blood glucose and plasma insulin were measured and glycoprotein components (protein bound hexose, protein bound hexosamine, fucose and sialic acid) in plasma, erythrocyte membrane, liver and kidney were investigated in control and experimental animals in each group. Oral administration of TpESet at a dose of 300 mg kg-1 b.wt. to diabetic animals for 45 days revert back all the altered biochemical parameters in diabetic animals. The present study thus, indicates that TpESet has potent role in modifying altered glycoprotein components in streptozotocin induced diabetic rats. |
| Uitgever: |
Asian Network for Scientific Information (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 27 van 32 gevonden artikelen
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