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Details for article 22 of 32 found articles
| Title: |
Pharmacokinetic Analysis of Warfarin in Iranian Warfarin Sensitive Patients |
| Author: |
S. Sadrai P. Ghadam R. Sharifian E. Nematipour Z. Kianmehr Sh. Shahriari |
| Appeared in: |
International journal of pharmacology |
| Paging: | Volume 4 (2008) nr. 2 pages 149-152 |
| Year: |
2008 |
| Contents: |
In this study, we investigated pharmacokinetic of warfarin in sensitive and control patients by HPLC. The analysis performed by HPLC consisted of a column (Perfectsil Target, 5 μm, 125x4.0 mm) and an isocratic mobile phase of methanol: acetonitrile: phosphate buffer (pH: 3.5) (7:55:38, v/v), flow rate: 1 mL min-1 and UV detection at 270 nm. The assay was linear in warfarin concentration ranges of 0.1-10 μg mL-1 (r2 = 0.9975) and with Relative Standard Deviation (RSD) of <8% for inter-day and <6% for intra-day. The mean warfarin blood concentration of 54 patients was 1.2 ± 0.6 μg mL-1. |
| Publisher: |
Asian Network for Scientific Information, Pakistan (provided by DOAJ) |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 22 of 32 found articles
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