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| Titel: |
Analgesic and Anti-Inflammatory Effects of Ethanolic Root Extract of Hippocratea africana |
| Auteur: |
Jude E. Okokon Bassey S. Antia Emem Umoh |
| Verschenen in: |
International journal of pharmacology |
| Paginering: | Jaargang 4 (2008) nr. 1 pagina's 51-55 |
| Jaar: |
2008 |
| Inhoud: |
The ethanolic root extract of Hippocratea africana (200-600 mg kg-1) was evaluated for analgesic, anti-inflammatory and antipyretic properties. The extract dose dependently inhibited acetic acid-induced writhing, formalin-induced paw licking and thermally -induced pain in mice. The extract also inhibited fresh egg albumin, carrageenin and xylene-induced inflammation in mice. These inhibitions were statistically significant (p<0.05) when compared to control. The roots extracts was also found to reduce pyrexia in rats. The analgesic, anti-inflammatory and antipyretic activities of the extract may be related to its active constituents such as tannins, saponins, steroid and flavonoids. |
| Uitgever: |
Asian Network for Scientific Information (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 3 van 22 gevonden artikelen
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