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| Titel: |
Mitochondrial Cardiac Energy Metabolism after One Treatment with Benzonidazole-Rochagan� |
| Auteur: |
D.A. Rendon |
| Verschenen in: |
International journal of pharmacology |
| Paginering: | Jaargang 2 (2006) nr. 6 pagina's 623-627 |
| Jaar: |
2006 |
| Inhoud: |
It was studied the mitochondrial parameters that characterized the mitochondrial cardiac energy metabolism after one treatment with benzonidazole-Rochagan�. The drug was given orally (100 mg benzonidazole/kg body weight) adult male Sprague-Dawley rats during nine consecutive days. The assayed mitochondrial parameters, using glutamate/malate and succinate as oxidative substrates, were the state 4, the state 3, the respiratory control, the efficiency of oxidative phosphorylation, the transmembrane electrical potential and the activity of the mitochondrial ATPsynthase. The results showed that all these mitochondrial parameters were not altered statistically after the above mentioned treatment, indicating that after this benzonidazole administration the mitochondrial cardiac energy metabolism was not altered. |
| Uitgever: |
Asian Network for Scientific Information (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 6 van 16 gevonden artikelen
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