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                                       Details for article 11 of 22 found articles
 
 
  Evaluation of in vivo Antiplasmodial Activity of Aspilia africana
 
 
Title: Evaluation of in vivo Antiplasmodial Activity of Aspilia africana
Author: Jude E. Okokon
Lucky L. Nwidu
Grace A. Essiet
Appeared in: International journal of pharmacology
Paging: Volume 2 (2006) nr. 3 pages 348-351
Year: 2006
Contents: The antiplasmodial activity of ethanol leaf extract of Aspilia africana was evaluated in mice infected with Plasmodium berghei berghei during early and established infections. Aspilia africana extract (100-300 mg kg-1 day-1) exhibited a significant (p<0.05) blood schizonticidal activity both in 4 day early infection and in established infection. The extract produced a significant (p<0.05) chemosuppression in both early and established infections tests though lower than that produced by chloroquine, 5 mg kg-1 day-1. Also, significant mean survival time was recorded in extract treated groups compared to the control group during established infection. The leaf extract posseses a promising antiplasmodial activity which can be exploited in malaria therapy.
Publisher: Asian Network for Scientific Information (provided by DOAJ)
Source file: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details for article 11 of 22 found articles
 
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