An antibacterial sesquiterpene lactone from fresh-water alga Vaucheria sessilis
Titel:
An antibacterial sesquiterpene lactone from fresh-water alga Vaucheria sessilis
Auteur:
Rosa Martha PÉREZ GUTIÉRREZ
Verschenen in:
Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas
Paginering:
Jaargang 8 (2009) nr. 4 pagina's 289-294
Jaar:
2009
Inhoud:
A sesquiterpene lactone 10B-Hydroxy-11BH-guai-12,6a-olide has been isolated from hexane extract of fresh-water alga Vaucheria sessilis using bioassay-guided fractionation. Its structure was established by a combination of spectroscopic methods and chemical correlation. The sesquiterpene lactone was assayed against Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Vibrio cholerae, Salmonella typhi and Kiebsiella pneumoniae. Disk-diffusion and the macrodilution methods were used as assay. The isolated compound inhibits growth of B. subtilis, B. cereus, E. coli, S. aureus and S. epidermidis in vitro with at a minimun inhibitory concentration (MIC) ranging from 25 to 50 ug/mL. It had no activity at 100 ug/mL against other bacterial species.
Uitgever:
Sociedad Latinoamericana de Fitoquímica (provided by DOAJ)
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