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| Titel: |
The role of dietary supplements in cytochrome P450-mediated drug interactions |
| Auteur: |
Jan L. Wahlstrom Robert S. Foti |
| Verschenen in: |
Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas |
| Paginering: | Jaargang 7 (2008) nr. 2 pagina's 66-84 |
| Jaar: |
2008 |
| Inhoud: |
Due in part to the increased consumption of herbal products on a global scale, a sharp rise in the reported number of both in vitro and in vivo interactions of herbals with prescription drugs that are metabolized by cytochrome P450 (CYP) enzymes has been observed. Popular products such as ginseng, saw palmetto and St. John¿s wort have demonstrated potent in vitro inhibition or induction of CYP activity. While reports of in vivo interactions are not as numerous, natural products such as garlic, goldenseal and grapefruit juice have shown the potential to affect CYP activity in vivo. As the wide-spread use of herbal and alternative medicines continues, an increased awareness on the part of the research and medical communities should afford safer use of these products in the future. |
| Uitgever: |
Sociedad Latinoamericana de Fitoquímica (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 4 van 5 gevonden artikelen
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