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  Indigenous plants and schistosomiasis control in south africa:molluscicidal activity of some zulu medicinal plants
 
 
Titel: Indigenous plants and schistosomiasis control in south africa:molluscicidal activity of some zulu medicinal plants
Auteur: John A. O. Ojewole
Verschenen in: Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas
Paginering: Jaargang 3 (2004) nr. 1 pagina's -8----22
Jaar: 2004
Inhoud: This work reviews plant molluscicides and presents preliminary findings of a molluscicidal screening programme carried out on some South African candidate molluscicidal plants. The overall objective of studies on plant molluscicides is to complement methods for controlling snails acting as intermediate hosts of schistosomes. In the last two decades, plant molluscicides have received considerable attention in the search for cheaper, effective, environmentally-friendly alternatives to expensive, imported chemotherapeutic agents and synthetic molluscicides used in schistosomiasis control. Although molluscicidal screening programmes have been conducted in many African countries, only relatively little efforts have been made to identify South African plants which could be suitable for use locally as plant molluascicides. The attraction of a locally grown molluscicidal plant is based on the development of a philosophy of selfreliance and community participation. This approach is dependent on community recognition of the infection as a public health menace, and their acceptance of the proposed control measures. Schistosomiasis has been recognized as a primary health problem in KwaZulu-Natal Province of South Africa, especially among the people in the rural communities that depend on river-water for all their water requirements. Concerns for schistosomiasis in the Province have indeed been matched by a 75% prevalence of Schistosoma haematobium infection among children aged 6 to 16 years. Forty-one medicinal plants commonly used by traditional healers for the treatment of schistosomiasis in KwaZulu-Natal Province of South Africa were evaluated for molluscicidal activity according to WHO¿s method, using niclosamide (BayluscideÒ) as reference molluscicide for comparison. Adult Bulinus africanus and Biomphalaria pfeifferi were exposed to sublethal and lethal doses of crude, aqueous extracts of the Zulu antischistosomal plants for a period of 24 hours. Results obtained indicate that 14 (
Uitgever: Sociedad Latinoamericana de Fitoquímica (provided by DOAJ)
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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