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| Titel: |
Clinico-bacteriology and risk factors for the diabetic foot infection with multidrug resistant microorganisms in north India |
| Auteur: |
Mohammad Zubair |
| Verschenen in: |
Biology and medicine |
| Paginering: | Jaargang 2 (2010) nr. 4 pagina's 22-34 |
| Jaar: |
2010 |
| Inhoud: |
This study was carried out in diabetic patients with foot ulcer, to determine the bacterial profile of infected ulcer,antibiotic resistance of the isolates and to find out the potential risk factors for infection with multidrug resistance.Gram-negative bacilli were screened for extended spectrum β lactamase (ESBL) production and Staphylococcusaureus were screened for methicillin resistance. In the 60 diabetic foot patients, 37(61.6%) were males and23(38%) were females. 49(81.6%) had T2DM, whereas only 11(18.3%) patients had T1DM. The presence ofsensory neuropathy was observed in 66.6% patients. Bacterial infection was found in 86.6% DFU cases, 40%cases had mixed bacterial infection while 48.5% cases had monomicrobial infections. 23.3% DFU patients hadinfection by multidrug resistant (MDR) organisms. ESBL producer was found in 45.3% gram-negative isolates. 33% gram-negative strains were positive for blaCTX-M gene followed by blaSHV (20%) and blaTEM (6.6%) Poorglycemic control in 63.3% patients, duration of infection > 1month (43.3%) and ulcer size > 4cm2 (78.1%) wasindependently associated with risk of MDR organism infection. |
| Uitgever: |
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| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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