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Details van artikel 10 van 14 gevonden artikelen
| Titel: |
Hypoglycemic of Cajanus scarabaeoides in glucose overloaded and streptozotocin-induced diabetic rats |
| Auteur: |
Suman Pattanayak, Siva Shankar Nayak, Durgaprasad Panda and Vikas Shende |
| Verschenen in: |
Bangladesh journal of pharmacology |
| Paginering: | Jaargang 4 (2009) nr. 2 pagina's 131-135 |
| Jaar: |
2009 |
| Inhoud: |
In light of traditional claim of Cajanus scarabaeoides (L) in the treatment of diabetes, we studied the effects of different solvent extracts in normal, glucose over loaded normal rats and streptozotocin-induced diabetic rats. The methanolic extract (500 mg/kg orally) was produce significantly reduce blood glucose level at normal, glucose over loaded normal rats, and streptozotocin-induced diabetic rats after 15 days treatment; whereas petroleum ether and chloroform extract (500 mg/kg orally) did not exhibit any significant effect on three groups of rats. Histopathology studies on pancreas of streptozotocin-induced diabetic rats shows inflammatory changes in pancreatic islets, results from selective destroy of insulin producing β-cells. These changes are inhibited by C. scarabaeoides methanolic extract and gliclazide. The antidiabetic activity of methanolic extract may be due to the presence of flavonoids. |
| Uitgever: |
Bangladesh Pharmacological Society (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 10 van 14 gevonden artikelen
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