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                                       Details for article 52 of 143 found articles
 
 
  ELECTROCHEMICAL STUDY OF THE INTERACTION OF DOXORUBICIN WITH ANIONIC SURFACTANTS (SODIUM LAURYL SULFATE)
 
 
Title: ELECTROCHEMICAL STUDY OF THE INTERACTION OF DOXORUBICIN WITH ANIONIC SURFACTANTS (SODIUM LAURYL SULFATE)
Author: Iuliana Serbanescu
Daniela Bulcu
Elena Volanschi
Appeared in: Analele Universitatii Bucuresti. Chimie
Paging: Volume XIV (2005) nr. I-II pages 369-376
Year: 2005
Contents: The interaction between an antitumoral drug, doxorubicin, and an anionic surfactant,sodium lauryl sulfate (SDS), is investigated by cyclic voltammetry. The cyclic voltammogramsrecorded in phosphate buffer (pH=7.09) in the presence of SDS indicate a shift of the peakpotentials of the first monoelectronic reversible couple towards negative values and a decrease ofthe cathodic peak current. Using non-linear fitting of the experimental data, values of the bindingconstant, K and 1:1 stoechiometry of the interaction were determined. The results outline a weakpredominantly electrostatic drug – surfactant interaction in the range of pre-micellar and micellarconcentrations of surfactant (SDS).
Publisher: Ars Docendi Publishing House (provided by DOAJ)
Source file: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details for article 52 of 143 found articles
 
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