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| Titel: |
Risk Factors for Bacteremia and Predictors of Mortality of Patients with Bloodstream Infection with Methicillin-Resistant Staphylococcus aureus |
| Auteur: |
Elcio Bakowski Sérgio Barsantini Wey Eduardo Alexandrino Servolo Medeiros |
| Verschenen in: |
American journal of infectious diseases |
| Paginering: | Jaargang 4 (2008) nr. 4 pagina's 262-266 |
| Jaar: |
2008 |
| Inhoud: |
The objective of this study was to evaluate the incidence of infection and the risk factors associated to bacteraemia and mortality due to Methicillin-Resistant Staphylococcus Aureus (MRSA).This cohort study, conducted from August 2004 through November 2005, involved 60 consecutively identified patients with bloodstream MRSA infection. The control group included 240 non-infected patients, randomly selected and hospitalized on the day, or immediately after, results of blood culture of case patients were available. A case-control (1:4) study was conducted for evaluation of risk factorsfor bacteraemia and death. The incidence of infection was 1.99/1000 admissions. Mortality rates were 30% among patients and 5.38% among controls, with an attributed death rate of 24.6%. Multivariateanalysis indicated the following risk factors for bacteraemia: severity predictors McCabe = 1, ASA>2 or APACHE II>10 (OR: 4.1; 95% CI: 1.8 - 9.4) and use of central venous catheter (OR: 7.3; 95% CI:2.4-22.2). University analysis showed as risk factors for mortality: age (OR: 1.08; 95% CI: 1.03-1.12), severity predictors McCabe = 1, ASA > 2 or APACHE II > 10 (OR: 9.13; 95% CI: 2.57-32.35), use ofmechanical ventilation (OR: 10.32; 95% CI: 1.78-59.51) and use of corticoids (OR: 9.96; 95% CI: 2.69-36.78). Our results when investigating risk factors for bacteremia and mortality due to MRSAshowed moderate influence of control group selection, in comparison to studies in which methicillinsensitive S. aureus infection is used as control. |
| Uitgever: |
Science Publications (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 9 van 10 gevonden artikelen
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