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| Titel: |
The Effect of a 4th Generation-Cephalosporin Introduction upon the Incidence of Multidrug-Resistant Gram-Negative Bacteria in a Non-Teaching Hospital |
| Auteur: |
Guilherme Henrique Campos Furtado Luciana Baria Perdiz Eduardo Alexandrino Servolo Medeiros |
| Verschenen in: |
American journal of infectious diseases |
| Paginering: | Jaargang 4 (2008) nr. 4 pagina's 267-271 |
| Jaar: |
2008 |
| Inhoud: |
Problem statement: Antimicrobial resistance is a worrisome situation in hospitals around the world and the misuse of certain classes of antimicrobials has contributed for this situation. Approach: We performed a prospective surveillance study on the incidence of multi-drug resistant bacteria before (phase 1) and after (phase 2) the introduction of a 4th-generation cephalosporin in anon-teaching hospital. Results: There was a significant reduction in the incidence of Enterobacter species (from 1.3 isolates per 100 patient-days to 0.39 isolates per 100 patient-days, p = 0.01) betweenthe two periods. We also observed a reduction in the consumption of ceftazidime (from 64.3 DDD per 1000 patient-days to 29.6 DDD per 1000 patient-days, p = 0.002) and ceftriaxone (from 323.9 DDD per 1000 patient-days to 246.2 DDD per 1000 patient-days, p = 0.01). Conclusion: The introduction of a 4th-generation cephalosporin in our setting resulted in an important reduction in the incidence of Enterobacter species. |
| Uitgever: |
Science Publications (provided by DOAJ) |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 10 van 10 gevonden artikelen
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