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Details van artikel 3 van 6 gevonden artikelen
| Titel: |
Limb anomalies and craniofacial syndromes II. Gene regulation of morphogenetic and dysmorphogenetic craniofacial mechanisms. |
| Auteur: |
F. N. Synodinos M. J. Papagrigorakis |
| Verschenen in: |
Hellenic orthodontic review |
| Paginering: | Jaargang 7 (2004) nr. 1 pagina's 59-89 |
| Jaar: |
2004 |
| Inhoud: |
It has been observed that the occurrence of craniofacial anomalies in many syndromes is accompanied by the manifestation of limb anomalies. A common denominator explaining the simultaneous presence of these anomalies may be revealed through the evolution of molecular biology and genetics. It is well known that, often, during embryogenesis, the same genes are expressed for the development of various anatomic structures, a fact recognized as economy of Nature. Analysis of the fundamental mechanisms involved in limb development and identification of corresponding craniofacial morphogenetic mechanisms constitute the first steps towards understanding the etiopathogenesis of anomalies concerning both limbs and craniofacial complex in many syndromes. The ultimate goal is the prevention and the effective management of such conditions. The aim of part II of this study is to describe, on the basis of contemporary literature, the craniofacial morphogenetic mechanisms emphasizing their possible relationship with respective mechanisms in limb development. |
| Uitgever: |
Greek Orthodontic Society |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 3 van 6 gevonden artikelen
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