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Details for article 10 of 14 found articles
| Title: |
In vitro metabolism of trenbolone: Study of the formation of covalently bound residues |
| Author: |
Evrard, P. Maghuin-Rogister, G. |
| Appeared in: |
Food additives and contaminants. Pt. A, Chemistry, analysis, control, exposure & risk assessment |
| Paging: | Volume 5 (1988) nr. 1 pages 59-65 |
| Year: |
1988-01 |
| Contents: |
In order to study the formation of bound residues of trenbolone, in vitro experiments were performed using bovine liver microsomes. These experiments showed that hepatic monooxygenases can generate reactive metabolites, which are able to bind to microsomal proteins or can be detoxified by conjugation to glutathione or to glutathione-S-transferases. Bioavailability and toxicological properties of these adducts are discussed. |
| Publisher: |
Taylor & Francis |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 10 of 14 found articles
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