Novel approach to control sulfamethazine misuse in food-producing animals by hair analysis
Titel:
Novel approach to control sulfamethazine misuse in food-producing animals by hair analysis
Auteur:
Gratacos-Cubarsi, M. Castellari, M. Valero, A. Diaz, I. Garcia-Regueiro, J. A.
Verschenen in:
Food additives and contaminants. Pt. A, Chemistry, analysis, control, exposure & risk assessment
Paginering:
Jaargang 23 (2006) nr. 10 pagina's 981-987
Jaar:
2006-10-01
Inhoud:
The presence of sulfamethazine residues in pig and calf hair was compared with the residual levels encountered in the corresponding edible tissues (liver and muscle) as a consequence of drug administration. Sulfamethazine up to 84.7 mg kg-1 was found in calf hair samples after a pharmacological treatment, with a significant effect of hair pigmentation. High concentrations of the parent drug were detected in calf hair for 4 weeks after administration, when sulfamethazine residues were no longer detectable in the corresponding edible tissues. In a similar way, pig hair also accumulated sulfamethazine residues up to 40.5 mg kg-1, which was more than the amount detected in the corresponding muscle and liver samples at slaughter. Hair analysis seems a suitable tool to improve the efficacy of regulatory controls, and thus the safety of the food chain and to discourage the improper use of sulfamethazine in animal farming.