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  Binding of aflatoxin B1 to cell wall components of Lactobacillus rhamnosus strain GG
 
 
Titel: Binding of aflatoxin B1 to cell wall components of Lactobacillus rhamnosus strain GG
Auteur: Lahtinen, S. J.
Haskard, C. A.
Ouwehand, A. C.
Salminen, S. J.
Ahokas, J. T.
Verschenen in: Food additives and contaminants. Pt. A, Chemistry, analysis, control, exposure & risk assessment
Paginering: Jaargang 21 (2004) nr. 2 pagina's 158-164
Jaar: 2004-02
Inhoud: The surface of Lactobacillus rhamnosus strain GG (LGG) has previously been shown to bind aflatoxin B1 (AFB1) effectively, it being a food-borne carcinogen produced by certain species of Aspergillus fungi. To establish which components of the cell envelope are involved in the AFB1 binding process, exopolysaccharides and a cell wall isolate containing peptidoglycan were extracted from LGG and its AFB1 binding properties were tested. LGG was also subjected to various enzymatic and chemical treatments and their effects on the binding of AFB1 by LGG were examined. No evidence was found for exopolysaccharides, cell wall proteins, Ca2+ or Mg2+ being involved in AFB1 binding. The AFB1 binding activity of the cell wall isolate indicates that AFB1 binds to the cell wall peptidoglycan of LGG or compounds tightly associated with the peptidoglycan.
Uitgever: Taylor & Francis
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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