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Details for article 1 of 8 found articles
| Title: |
A mathematical model of a micrometasasis |
| Author: |
Bloor, Malcolm I. G. Wilson, Michae. J. |
| Appeared in: |
Computational & mathematical methods in medicine |
| Paging: | Volume 1 (1997) nr. 2 pages 153-168 |
| Year: |
1997 |
| Contents: |
Experimental evidence indicates that tumour metastases can exist for long periods in a dormant state, with cell proliferation balancing cell death. However, this balance can be upset, by removing the primary tumour for instance, which causes the metastasis to grow, or by adminstering a substances inhabiting angiogenesis which causes the metastasis toi regress. A mathematical model is presented for the growth of a tumour metastasis, which by postulating the possibility of a local imbalance between cell proliferation and cell death though apoptosis, is able to explain some of these observations. A prediction of the model is that at any position within the metastasis there will be a radial movement of cells, even in the document state. |
| Publisher: |
Taylor & Francis |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 1 of 8 found articles
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