|
| << vorige | volgende >> |
Tijdschrift beschrijving
Alle jaargangen van het bijbehorende tijdschrift
Alle afleveringen van het bijbehorende jaargang
Alle artikelen van de bijbehorende aflevering
Details van artikel 5 van 37 gevonden artikelen
| Titel: |
Density functional study on formation of A and B rings in conversion of 2,3-oxidosqualene to lanosterol |
| Auteur: |
Hess, B. Andes Smentek, Lidia |
| Verschenen in: |
Molecular physics |
| Paginering: | Jaargang 102 (2004) nr. 11-12 pagina's 1201-1206 |
| Jaar: |
2004-06-10 |
| Inhoud: |
A density functional computational study has been performed on a model system for the formation of the A and B rings in the oxidosqulene cyclase pathway for the cyclization of squalene to lanosterol. Unlike what had previously been found for the squalene hopene cyclase pathway, the formation of the A and B rings was found not to be concerted. Two intermediates were located on the reaction pathway during the formation of the B ring, though they were found to be very shallow minima on a quite flat part of the potential surface. It is unlikely that in the enzymatic pathway these intermediates would play an important role, if indeed they exist at all. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 5 van 37 gevonden artikelen
| << vorige | volgende >> |