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| Titel: |
A study of lipid profile and apolipoproteins A1 and B: their relationship to aggression and psychopathology in male patients with psychosis |
| Auteur: |
Chakrabarti, Nandini Sinha, VK Sinha, Baxi Neeraj Prasad |
| Verschenen in: |
The journal of forensic psychiatry & psychology |
| Paginering: | Jaargang 15 (2004) nr. 2 pagina's 314-324 |
| Jaar: |
2004-06 |
| Inhoud: |
High cholesterol has been unequivocally put forward as the most important factor in the development of coronary artery disease. Yet a body of evolving data yields evidence of the hazards of low cholesterol, including links to aggression, psychopathology and hostility. The aim of the present study was (1) To compare the serum lipid profile and serum apolipoproteins A1 and B of psychotic patients with a violent criminal record and psychotic patients with no history of violence. (2) To find a relationship, if any, between the lipid and apolipoprotein profile and psychopathology of the participants of the study. Fasting blood samples were collected from 30 psychotic in-patients with a known history of violent crime and 30 in-patients with no history of violence. Serum lipid profile and serum apolipoproteins A1 and B were estimated from each sample. The biochemical values were compared between the two groups. Correlations between the biochemical parameters and scores of psychopathology (as per expanded BPRS Scale) were also studied. The group with a criminal record showed significantly lower total cholesterol, lower LDL cholesterol, higher apolipoprotein A1 and lower apolipoprotein B compared to the study group without a history of violence. Significant correlations were also found between some of the scores of psychopathology and biochemical parameters. Lower total cholesterol, lower LDL cholesterol, higher apolipoprotein A1 and lower apolipoprotein B could predispose to violence. Such findings hold important implications for a society where low cholesterol and higher apo A1 : apo B ratio has come to be the norm of the day. |
| Uitgever: |
Routledge |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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