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| Titel: |
Comparison of the delayed neurotoxicity of O-methyl and O-ethyl analogs of EPN, leptophos, and cyanofenphos |
| Auteur: |
Francis, B. Magnus Hansen, Larry G. Metcalf, Robert A. Metcalf, Robert L. |
| Verschenen in: |
Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes |
| Paginering: | Jaargang 17 (1982) nr. 6 pagina's 611-633 |
| Jaar: |
1982 |
| Inhoud: |
Eight pairs of O-methyl and O-ethyl O-(substituted-phenyl) phenylphosphonothionates were evaluated with respect to their delayed neurotoxic activity in hens. O-methyl compounds were in all cases more active than their O-ethyl analogs. The neurotoxic potential of the O-methyl phenylphosphonothionates was 2,5-diCl >4-NO2 >2,4,5-triCl and 2,4,6-triCl >2,4-diCl >2,5-diCl-4-Br >4-CN, when single oral doses were given. Both EPN-ethyl and leptophos-raethyl were more neurotoxic in multiple dermal than multiple oral dosing regimens. LD50s for mice and flies were established. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 3 van 10 gevonden artikelen
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