The effect of acute administration of the mycotoxin zearalenone to female pigs
Title:
The effect of acute administration of the mycotoxin zearalenone to female pigs
Author:
Farnworth, E. R. Trenholm, H. L.
Appeared in:
Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes
Paging:
Volume 16 (1981) nr. 3 pages 239-252
Year:
1981
Contents:
Crystalline zearalenone was administered to young female pigs at dose levels of 0, 3.5, 7.5 and 11.5 mg zearalenone/kg body weight. All animals receiving the mycotoxin exhibited vulva vag-initis and had enlarged reproductive tracts, 1 week after dosing. Free zearalenone was found in the blood, feces and urine of dosed animals. The highest zearalenone level detected was 2.61 ng/ml from a pig that received the 7.5 mg/kg dose. After 24 hours, feces collected contained on average up to 308 ng zearalenone per g of dried feces. Zearalenone levels of up to 59 ng/ml, and a -zearalenol levels of up to 155 ng/ml urine were found. ss -zearalenol was also detected in the urine.
Journal description