Behavioral effects of methyl parathion and toxaphene exposure in rats
Titel:
Behavioral effects of methyl parathion and toxaphene exposure in rats
Auteur:
Crowder, L. A. Lanzaro, G. C. Whitson, R. S.
Verschenen in:
Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes
Paginering:
Jaargang 15 (1980) nr. 4 pagina's 365-378
Jaar:
1980
Inhoud:
The behavior of rats exposed peri- and postnatally to methyl parathion (MP) and toxaphene (T) was examined with a variety of maturational and learning tests. Females received daily oral doses of 1.0 mg/kg MP or 1.0 mg/kg MP + 2.0 mg/kg T between Days 7-15 of pregnancy. With T alone, rats of the postnatal group were dosed daily with 6 mg/kg for 21 days,.while in the perinatal study females received 6 mg/kg daily from Day 7 of pregnancy until parturition. Rat pups exposed to sublethal doses of MP and T in combination or alone demonstrated few significant changes in learning ability as measured by a simple two-choice maze, motor skills, or behavior.