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The elimination, distribution, and metabolism of 14C-toxaphene in the pregnant rat
Titel:
The elimination, distribution, and metabolism of 14C-toxaphene in the pregnant rat
Auteur:
Pollock, G. A. Hillstrand, R.
Verschenen in:
Journal of environmental science and health. Part B, Pesticides, food contaminants, and agricultural wastes
Paginering:
Jaargang 17 (1982) nr. 6 pagina's 635-648
Jaar:
1982
Inhoud:
Pregnant Sprague-Dawley rats were orally administered toxaphene in olive oil on day 15 of pregnancy and housed in glass metabolism cages. Urine, feces, and tissues were collected and assayed for radioactivity. The elimination was similar to that in virgin females with the majority of activity excreted in the feces (38.4%; five days) and less in the urine (23.7%; five days). The fetuses contained the lowest levels of radioactivity of all tissues tested (28 ppb; five days) and fat contained the highest levels (7476 ppb; five days). A comparison of the activity in the fetuses with that in the dam's fat showed slight differences, indicating the presence of more polar compounds (perhaps metabolites).
Uitgever:
Taylor & Francis
Bronbestand:
Elektronische Wetenschappelijke Tijdschriften
Details van artikel 240 van 262 gevonden artikelen
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