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Details for article 12 of 16 found articles
| Title: |
Influence of some pesticides on activity of seven serum enzymes (in vitro) |
| Author: |
Sekeroglu, M. Ramazan Celi˙k, Ismail Arslan, Oktay |
| Appeared in: |
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering |
| Paging: | Volume 32 (1997) nr. 7 pages 1975-1980 |
| Year: |
1997-08 |
| Contents: |
The purpose of this study was to investigate the effects of Endosulfan [6,7,8,9,10, 10-hexachloro- 1,5. 5a. 6, 9, 9 a hexahydro- 6, 9 methano - 2, 4, 3-benzo (e) dioxathpiepin 3- oxide ], Mavrik [α-cyano -3-phenoxybenzyl M - (2 chloro-α-α-α-triflouro-p-tolyl) - D - valinate ], 2,4-D (2,4-Dichlorophenoxyacetic acid) and Neoran (isopropyl -4,4-dibromobenzilate) on serum amylase (EC 3.2.1.1), creatine kinase (CK; EC 2.7.3.2) aspartate amino transferase (AST; EC 2.6.1.1), alanine aminotransferase (ALT; EC 2..6.1.2), alkaline phosfatase (ALP; EC 3.1.3.1), gamma glutamyl transferase (GGT; EC 2.3.2.2) and lactate dehydrogenase (LDH; EC 1.1.1.27). I50 values of chemicals caused inhibition were determined by means of activity percentage -[I] diagrams. Endosulfan had effect of inhibition only on AST. The I50 value of chemical was determined as 3.13×10-4 M. Mavrik had effects of inhibition on AST, ALT, ALP and LDH. The values of I50 were 7.83×10-4 M, 1.17×10-4, 1.23×10-3 M and 2.23×10-3 M, respectively. 2,4-D had effects of inhibition on ALT, ALP, GGT and LDH. The I50 values of chemical were 6.97×10-2 M, 5.05×10-2 M, 2.35×10-2 M, 1.07×10-2 M, respectively. On the other hand, Neoran had effects of inhibition of all enzymes except amylase. I50 values of this compound on other enzymes (CK, AST, ALT, ALP, GGT and LDH) were 4.41×10-4 M, 5.06×10-3M, 2.40×10-3M, 5.23×10-3M ,4.4×10-3 M, 5.97×10-3 M, respectively. |
| Publisher: |
Taylor & Francis |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 12 of 16 found articles
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