The effects of five widely used pesticides on erythrocytes of the Dorset sheep, an animal model with low erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) activity
Title:
The effects of five widely used pesticides on erythrocytes of the Dorset sheep, an animal model with low erythrocyte glucose-6-phosphate dehydrogenase (G-6-PD) activity
Author:
Geiger, Christopher P. Calabrese, Edward J.
Appeared in:
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
Paging:
Volume 20 (1985) nr. 5 pages 521-527
Year:
1985-07
Contents:
The in vitro effects of five widely employed pesticides (i.e., insecticides: malathion and aldicarb; herbicides: diuron, metolachlor, and glyphosate) on the occurrence of oxidative stress [i.e., increased levels of methemoglobin (METHB) amd decreased levels of induced glutathione (GSH)] in erythrocytes from female Dorset sheep, an animal model with low erythrocyte G-6-PD activity. The only statistically significant treatments (p 0.05) occurred with malathion and metolachlor which reduced GSH levels at the highest concentration (i.e., 100 ppm) employed by 59% and 45%, respectively.
Journal description